Bottle of MEDICUBE US Retinol NMN Boosting Serum with a sleek pump dispenser on a white background.

Medicube US Retinol NMN Boosting Serum in a sleek glass bottle, featuring a dropper applicator and clear labeling.

MEDICUBE US Retinol NMN Boosting Serum in a sleek glass bottle, showing the serum's smooth texture and minimalist packaging.

MEDICUBE US Retinol NMN Boosting Serum in a glass bottle, with a pump dispenser, showing the serum's smooth, clear liquid.

MEDICUBE US Retinol NMN Boosting Serum in a sleek bottle, showing the serum's smooth, clear texture and modern packaging.

Medicube US Retinol NMN Boosting Serum in a clear glass bottle with a pump dispenser, shown on a white background.

MEDICUBE US Retinol NMN Boosting Serum bottle, clear glass container with dropper for skincare application.

MEDICUBE US Retinol NMN Boosting Serum in a sleek glass bottle with a pump dispenser, placed on a neutral background.

Medicube Retinol NMN Boosting Serum(30ml)

Name: Medicube Retinol NMN Boosting Serum(30ml)
Rating: 4.95 (37 reviews)

£25.99 GBP

£49.00 GBP

Taxes included.

17 people viewing this right now

Stock Only -- left

Order within to ship today

🏷️

Spend £50+ & Get Extra 10% off

SKINZA10

Secure Checkout

About Product

Want serious anti-ageing results without the irritation that usually comes with high-strength Retinol?

The Medicube Retinol NMN Boosting Serum makes it possible. Powered by 99.8% purity patented Retinol-some™ at 1.9% concentration and 99% purity NMN (Nicotinamide Mononucleotide), this low-irritation serum targets fine lines, wrinkles and enlarged pores while supporting natural skin firmness — giving skin a visibly bouncier, smoother and more resilient look.

Retinol-some™ is Medicube's patented encapsulation technology — Retinol is wrapped in a biomimetic lipid capsule (using Cholesterol, Rapeseed Sterols, Phytosterols and Palm Oil) that protects it from oxidation, improves its stability and releases it gradually for effective delivery with significantly reduced risk of irritation. NMN (Nicotinamide Mononucleotide) is a cellular energy precursor drawn from longevity science — it supports NAD+ production within skin cells, boosting the skin's own regeneration capacity, improving firmness and contributing to a healthier, more radiant complexion.

The 5-Synergy Complex amplifies the formula: Peptides stimulate collagen and support skin structure, Ceramide NP + Cholesterol + Squalane strengthen the moisture barrier, a Probiotic Ferment Trio (Bifida, Lactobacillus, Lactococcus) supports the microbiome, Beta-Glucan soothes and protects, and Retinal (in addition to Retinol) adds an extra layer of Vitamin A activity. Niacinamide brightens and refines pores. Panthenol and Allantoin calm and repair. Adenosine reduces fine lines. Macadamia Oil and Tocopherol nourish and protect.

Clinically tested — smile lines improved by 11%, pore-area firmness +2.8% and surface hydration +13.6% after just 2 weeks. Hypoallergenic and non-comedogenic.

NOT safe during pregnancy or breastfeeding.

How To Use

Use in the evening only after cleansing and toning. Retinol is sensitive to light and heat — nighttime application is essential.

Week 1–2 (Adjustment Period): Apply 1–2 drops to targeted areas (around the eyes, smile lines, forehead) 2–3 times per week only.

Week 3+: Increase to every other evening as tolerated, then build to nightly use as your skin adapts.

Follow with moisturiser. Always apply SPF 30+ every morning while using this serum, even on days you didn't use it the night before — Retinol remains active in the skin.

Do not use in the same routine as AHA, BHA or Vitamin C exfoliants. Patch test recommended before full use.

Key Benefits

99.8% purity Retinol-some™ 1.9% — patented encapsulated Retinol for effective, low-irritation delivery
99% purity NMN — cellular energy precursor that supports skin regeneration, firmness and radiance
Retinal — additional Vitamin A active for enhanced cell renewal
5-Synergy Complex — Peptides + Ceramide NP + Probiotics + Beta-Glucan + Antioxidants
Niacinamide — brightens, refines pores, supports barrier
Ceramide NP + Cholesterol + Squalane + Phytosterols — restores and reinforces the moisture barrier
Probiotic Ferment Trio (Bifida, Lactobacillus, Lactococcus) — microbiome support, soothes adjustment reactions
Panthenol + Allantoin — calms and repairs throughout Retinol cycling
Adenosine — clinically approved anti-ageing active
Clinically tested: +11% smile line improvement, +2.8% pore firmness, +13.6% surface hydration in 2 weeks
Hypoallergenic, non-comedogenic, suitable for sensitive and acne-prone skin when introduced gradually

Skin Type

All skin types including sensitive and acne-prone. Hypoallergenic and non-comedogenic. Introduce gradually during the adjustment period.

NOT safe during pregnancy or breastfeeding. Retinol is not recommended during pregnancy. Always consult your GP or midwife before use.

Ingredients

Water, Glycereth-26, Niacinamide, Glycerin, Caprylic/Capric Triglyceride, Water, Caprylic/Capric Triglyceride, Macadamia Ternifolia Seed Oil, Butylene Glycol, Hydrogenated Lecithin, Retinol, Brassica Campestris (Rapeseed) Sterols, Glycerin, 1,2-Hexanediol, Cholesterol, Polyglyceryl-10 Laurate, Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate, Aluminum/Magnesium Hydroxide Stearate, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Potassium Cetyl Phosphate, Tris(Tetramethylhydroxypiperidinol) Citrate, Glyceryl Citrate/Lactate/Linoleate/Oleate, Elaeis Guineensis (Palm) Oil, 1,2-Hexanediol, Cetyl Ethylhexanoate, Hydroxyacetophenone, Ammonium Acryloyldimethyltaurate/VP Copolymer, Polyacrylate Crosspolymer-6, Aluminum Starch Octenylsuccinate, Glycerin, Retinal, Squalane, Water, Polyquaternium-51, Tocopherol, Panthenol, Allantoin, Adenosine, Disodium EDTA, Water, Bifida Ferment Lysate, Lactobacillus Ferment Lysate, Lactococcus Ferment Lysate, Dipropylene Glycol, Niacinamide, 1,2-Hexanediol, Beta-Glucan, Ceramide NP, Nicotinamide Mononucleotide

FAQ'S

What is Retinol-some™?
Medicube's patented technology that encapsulates Retinol in a biomimetic lipid capsule — protecting it from degradation, improving absorption and releasing it gradually. The result is clinical-strength Retinol activity with significantly reduced irritation risk, making this suitable even for sensitive and acne-prone skin.

What is NMN and why is it in a serum?
NMN (Nicotinamide Mononucleotide) is a cellular energy precursor that supports NAD+ production in skin cells. NAD+ is essential for skin cell repair and regeneration — NMN essentially helps your skin's own renewal systems work more efficiently, improving firmness, texture and radiance over time.

Is it suitable for Retinol beginners?
Yes — the patented encapsulation technology and 5-Synergy Complex make this one of the most accessible high-strength Retinol serums available. Follow the adjustment protocol: start 2–3 times per week and build up gradually.

Do I need SPF?
Yes — always. Apply SPF 30+ every morning during the period you are using this serum, even on days you skipped it the night before.

Is it pregnancy-safe?
No. Retinol is not recommended during pregnancy or breastfeeding. Do not use if pregnant or nursing.

How quickly will I see results?
Clinical testing shows smile lines improved by 11%, pore-area firmness +2.8% and surface hydration +13.6% after just 2 weeks. Longer-term improvements in texture, tone and firmness build progressively over 4–8 weeks.

5 stars: 36 (97%)
4 stars: 0 (0%)
3 stars: 1 (3%)
2 stars: 0 (0%)
1 star: 0 (0%)

My skin feels renewed. It’s firmer, brighter, and much smoother. This serum is a game changer.

Everything about this is 5-star. The texture, the results, and the price. Will definitely keep buying.

I feel much more confident in my skin now. The fine lines are barely visible and the glow is amazing.

It’s strong enough to see results but gentle enough for nightly use. My skin has never looked better.

I’ve tried the big brands, but this works much better for my skin. Exceptional quality and fast delivery.

It has helped with my hormonal breakouts as well as aging. A fantastic multi-tasking serum.

My skin is so soft to the touch. It’s rare to find a retinol that improves texture this quickly.

This has cleared up my texture issues almost entirely. My face is so smooth now. Thank you Skinza!

I look more awake and refreshed. The NMN really helps with skin fatigue. A must-have for busy people.

My dark spots are fading and my overall complexion is much more unified. It’s an amazing all-rounder.

I won't use any other retinol now. This is the perfect balance of strength and comfort. 10/10 recommendation.

The packaging is sleek and the serum feels like silk. It’s a joy to use every night. My skin is glowing.

The NMN boost is fantastic. My skin looks energized and less tired, even after a long week. Simply brilliant.

The difference in my skin is worth the investment. It’s clearer, smoother, and much younger looking.

I am very picky with skincare, but this has exceeded my expectations. My pores are virtually invisible now.

I've had no peeling or dryness at all. It's the most comfortable retinol I've ever used. Great for my daily routine.

It leaves my face feeling nourished and cared for. It’s not just an active serum; it feels like a full treatment.

I can really feel the lifting effect. My jawline looks more defined and my skin feels much more elastic.

It does exactly what it says on the bottle. My skin feels tighter and much more vibrant. Will definitely buy again.

Feels like a salon treatment at home. My skin texture is so much more refined. This is a solid investment for your face.

A little goes a long way and the quality is far superior to other brands at this price point. My skin looks great.

So glad I discovered this. It’s effective, gentle, and the results are visible within just a week of nightly use.

Every morning my skin looks better. The fine lines on my forehead are definitely fading. I'm very impressed with this brand.

It gives such a lovely healthy glow. My face feels rejuvenated and I've had so many compliments lately on my skin.

My skin feels like velvet. It absorbs so well and doesn't cause any breakouts. Highly recommend for anyone looking for anti-aging.

I was worried about retinol burn, but this is so well-formulated. My skin is calm, clear, and looking better every day.

I'm in my 50s and this has helped my skin elasticity more than expensive designer creams. Truly a brilliant formula.

You can tell this is premium skincare. The ingredients are top-notch and the results speak for themselves. My pores look much smaller too.

I'm amazed at how fast this worked. My skin feels firmer and the overall tone is much brighter. Best anti-aging find this year.

Unlike other retinols that dry me out, this one keeps my skin hydrated and happy. The NMN really seems to boost the overall health of my face.

I tell everyone about this serum now. It has completely transformed my dull skin into something radiant and firm. Absolutely love it!

The serum itself is 5 stars and works wonders for my skin, but the delivery box arrived completely crushed and open. Please improve shipping protection.

I have sensitive skin and usually struggle with retinol, but this serum is so soothing. The boosting effect is real—my skin has a healthy glow.

It sinks in immediately and doesn't feel sticky. I use it every night and wake up with much clearer, tighter skin. Fantastic quality product.

SKINZA PRODUCTS

Popular searches

BEST SELLER